Introduction: Juvenile nasopharyngeal angiofibroma is a rare, highly .. Luiz A CR, Romualdo S LT, Fava A S. Angiofibroma nasofaríngeo: revisão de literatura. Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor arising predominantly in the nasopharynx of adolescent males. It is an aggressive. Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas.

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Several surgical approaches have been utilized for the removal of nasopharyngeal angiofibromas, including transnasal, transpalatal, transzygomatic, and transcervical accesses, in addition to lateral rhinotomy and mid-facial degloving, with or without extension to the upper lip or concomitant craniotomy 9. JNA being an aggressive tumor may recur posttreatment. Nasal cavity Esthesioneuroblastoma Nasopharynx Nasopharyngeal carcinoma Nasopharyngeal angiofibroma Larynx Laryngeal cancer Laryngeal papillomatosis.

Find articles by Arlete Angiogibroma Granizo Santos. They may be locally aggressive. Studies comparing surgical treatment with or without embolization have shown that preoperative embolization reduced intraoperative blood loss and the need for replacement of blood products 31 Olfactory neuroblastoma Olfactory neuroblastoma.

Angiofibroma nasofaríngeo juvenil

To remove the tumor in two patients, the tumor section was performed in two halves, the largest of which was removed by transoral route. The mean operation time was min, and the mean bleeding volume was mL. To retrospectively angikfibroma our experience in the diagnosis and treatment of patients with juvenile nasopharyngeal angiofibroma. We analyzed findings naosfaringeo 20 patients who underwent surgery between and Preoperative embolisation of tumour may be of some use in reducing intraoperative bleeding.

The main clinical presentation of JNA is unilateral nasal obstruction with or without epistaxis. He also complained of difficulty in breathing since 6—7 months.


No encapsulation was noted [ Figure 4 ].

Juvenile nasopharyngeal angiofibroma

Although nasal endoscopic surgery is safe, rapid, and effective, studies are needed to assess the importance of preoperative embolization and clamping of the external carotid artery in reducing intraoperative bleeding. Long-term tumor recurrence has been reported due to incomplete initial resection. Efforts to determine the pathogenesis of the tumor have been done by studying xngiofibroma expression of various growth factors and oncogenes such as C-KIT and C-MYC. However, as in any invasive procedure, embolization presents risks that should be fully explained to the patients They may extend towards the nasopharynx, which includes the maxillary, ethmoid, and sphenoid sinuses.

He underwent a tracheotomy prior to secure the airway by provisional character. We can see that this technique allows easier resection of large tumors staged as SCI.

Nasopharyngeal Angiofibroma: Review of the Genetic and Molecular Aspects

Treatment trends in patients during 40 years. This website is intended for pathologists and laboratory personnel, nasofarinteo understand that medical angiofibgoma is imperfect and must be interpreted using reasonable medical judgment.

Consistent with previous results, we found that the mean operation time in the 17 patients who underwent endoscopic surgery alone was min Of our 20 patients, only 2 underwent surgery without embolization, with these 2 showing significantly greater intraoperative bleeding than the 18 patients who underwent embolization.

Blood vessels were seen in large number at the periphery of the lesion [ Figure 5 ]. National Center for Biotechnology InformationU. This deception has brought us more space for access to tumor All surgeries were performed under general anesthesia, days after angiography with embolization of the tumor.


Juvenile nasopharyngeal angiofibroma originates in the sphenopalatine forame, causing epistaxes and nasal obstruction. Patients undergoing embolization require external carotid clamping due to collateral circulation, which can increase bleeding. The recurrence rate of endoscopically resected tumors has been shown to be low, and we found that none of our 20 patients experienced tumor recurrence.

Recurrence in juvenile angiofibroma.

Recurrence in juvenile angiofibroma. Similarly, our patients ranged in age from 10 to 29 years, with a mean age of 16 years, and all were male.

We started the first surgical dissection of the tumor through a unciform process incision, anterior and posterior nsofaringeo with wide exposure of the lamina papyracea and the ethmoid roof. Classification of Fisch Type I: Endoscopic approach is an excellent tool in primary and recurrent JNA, it allows visualisation and precise removal of the lesion.

Nasopharyngeal angiofibroma: Our experience and literature review

Arterial embolization in the management of posterior epistaxis. Arch Otolaryngol Head Neck Surg.

Tissue maturation during the growth of juvenile nasopharyngeal angiofibroma. Endoscopic Surgery for Juvenile Angiofibroma: Endoscopic Ressection of Juvenile Angiofibroma: In angiofivroma of the existing controversy, the hormonal stimulation means remains a JNA therapeutic possible target. Endoscopic Ressection of Juvenile Angiofibroma. Conclusion Nasal endoscopy, alone or combined with open techniques, was safe for the resection of angiofibromas at different stages, with low morbidity and high efficacy, as shown by complete tumor removal and low recurrence rates.

Clinical examination reveals a firm and friable mass in the nasopharynx and nose.